{"id":9075,"date":"2026-11-06T11:25:11","date_gmt":"2026-11-06T11:25:11","guid":{"rendered":"https:\/\/drkozarevcosmedics.com\/?p=9075"},"modified":"2026-11-06T11:28:47","modified_gmt":"2026-11-06T11:28:47","slug":"gubitak-cvrstine-koze-posle-40","status":"publish","type":"post","link":"https:\/\/drkozarevcosmedics.com\/en\/gubitak-cvrstine-koze-posle-40\/","title":{"rendered":"Za\u0161to ko\u017ea gubi \u010dvrstinu posle 40. godine i \u0161ta zaista mo\u017ee da pomogne?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"9075\" class=\"elementor elementor-9075\">\n\t\t\t\t<div class=\"elementor-element elementor-element-97a5d79 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"97a5d79\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-7db5a4a flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"7db5a4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Mo\u017eda si primetila da ko\u017ea na obrazima vi\u0161e nema istu puno\u0107u, da su fine linije izra\u017eenije ili da kontura donje vilice izgleda druga\u010dije nego pre nekoliko godina. Krema koju si dugo koristila i dalje pru\u017ea ose\u0107aj hidratacije, ali vi\u0161e nema isti efekat na izgled ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Ove promene \u010desto opisujemo kao gubitak \u010dvrstine i elasti\u010dnosti, iako se iza njih nalazi nekoliko razli\u010ditih procesa. Sa godinama se menjaju struktura kolagena i elasti\u010dnih vlakana, sposobnost ko\u017ee da zadr\u017eava vodu, ali i raspored tkiva koje licu daje volumen. Kod \u017eena u perimenopauzi dodatnu ulogu mogu imati hormonalne promene.<\/span><\/p><p><span style=\"font-weight: 400;\">Razumevanje tih procesa poma\u017ee nam da razlikujemo ono \u0161to se mo\u017ee pobolj\u0161ati pravilnom negom od promena koje zahtevaju druga\u010diji dermatolo\u0161ki pristup. Zato \u0107emo prvo objasniti \u0161ta ko\u017ei daje \u010dvrstinu i \u0161ta se sa tim strukturama doga\u0111a tokom godina.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-aac1c6c thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"aac1c6c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-b4ad4ab flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"b4ad4ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u0160ta ko\u017ei daje \u010dvrstinu i elasti\u010dnost?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-256c6c9 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"256c6c9\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-842463b flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"842463b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Za \u010dvrstinu i elasti\u010dnost ko\u017ee posebno je va\u017ean dermis, sloj koji se nalazi ispod epidermisa. U njemu se nalazi slo\u017eena mre\u017ea kolagena, elasti\u010dnih vlakana i drugih molekula koji zajedno \u010dine ekstracelularni matriks.<\/span><\/p><p><span style=\"font-weight: 400;\">Kolagen pru\u017ea ko\u017ei mehani\u010dku potporu i otpornost na istezanje, dok joj elasti\u010dna vlakna omogu\u0107avaju da se nakon pokreta vra\u0107a prema prvobitnom obliku. Hijaluronska kiselina i drugi glikozaminoglikani vezuju vodu i doprinose hidrataciji i fizi\u010dkim svojstvima tkiva.<\/span><\/p><p><span style=\"font-weight: 400;\">Za odr\u017eavanje ove strukture odgovorni su fibroblasti, \u0107elije koje stvaraju i obnavljaju veliki deo komponenti ekstracelularnog matriksa. Tokom \u017eivota one neprekidno u\u010destvuju u stvaranju novih i remodelovanju postoje\u0107ih vlakana.<\/span><\/p><p><span style=\"font-weight: 400;\">Sa godinama se aktivnost fibroblasta menja, a struktura matriksa postaje druga\u010dija. Kolagenska mre\u017ea postepeno gubi deo svoje organizacije, dok elasti\u010dna vlakna mogu postati manje funkcionalna. Zbog toga ko\u017ea mo\u017ee delovati tanje, manje \u010dvrsto i sporije se vra\u0107ati nakon istezanja.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a8e775b thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"a8e775b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-c78827e flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-image\" data-id=\"c78827e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" width=\"1024\" height=\"683\" src=\"https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-1024x683.jpg\" class=\"attachment-large size-large wp-image-9133\" alt=\"gubitak elasticnosti koze\" srcset=\"https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-1024x683.jpg 1024w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-300x200.jpg 300w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-768x512.jpg 768w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-1536x1024.jpg 1536w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-2048x1365.jpg 2048w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-18x12.jpg 18w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-miriam-alonso-7623581-600x400.jpg 600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b746233 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"b746233\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u0160ta se de\u0161ava sa kolagenom posle 40?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a76504c thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"a76504c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-9438a44 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"9438a44\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Kolagen se tokom \u017eivota neprekidno stvara i razgra\u0111uje. Fibroblasti proizvode nove kolagenske molekule, dok posebni enzimi u\u010destvuju u remodelovanju postoje\u0107ih vlakana. Zahvaljuju\u0107i toj ravnote\u017ei, dermis mo\u017ee da odr\u017eava svoju strukturu i prilago\u0111ava se promenama u tkivu.<\/span><\/p><p><span style=\"font-weight: 400;\">Sa starenjem se smanjuje sposobnost fibroblasta da odr\u017eavaju kolagensku mre\u017eu na isti na\u010din kao ranije. Istovremeno se menjaju kvalitet, raspored i me\u0111usobne veze kolagenskih vlakana. Posledica je postepeno smanjenje mehani\u010dke potpore koju dermis pru\u017ea ko\u017ei.<\/span><\/p><p><span style=\"font-weight: 400;\">Na ove procese sna\u017eno uti\u010de UV zra\u010denje. Ono mo\u017ee pokrenuti stvaranje reaktivnih molekula i aktivirati signalne puteve koji pove\u0107avaju aktivnost matriksnih metaloproteinaza, enzima koji u\u010destvuju u razgradnji komponenti ekstracelularnog matriksa. Kada je ko\u017ea godinama izlo\u017eena suncu, takvi procesi doprinose nastanku bora i promenama njene teksture i \u010dvrstine.<\/span><\/p><p><span style=\"font-weight: 400;\">Kod \u017eena se u \u010detrdesetim i pedesetim godinama mo\u017ee pridru\u017eiti jo\u0161 jedan faktor. Estrogen u\u010destvuje u regulaciji metabolizma kolagena, a njegov pad tokom menopauzalne tranzicije povezan je sa smanjenjem sadr\u017eaja kolagena i promenama debljine i elasti\u010dnosti ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Pregled istra\u017eivanja o menopauzalnim promenama ko\u017ee, objavljen u medicinskoj literaturi dostupnoj preko ameri\u010dke <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12374573\/\"><span style=\"font-weight: 400;\">Nacionalne medicinske biblioteke<\/span><\/a><span style=\"font-weight: 400;\">, opisuje povezanost pada estrogena sa promenama kolagena, hidratacije i elasti\u010dnosti.<\/span><\/p><p><span style=\"font-weight: 400;\">Zbog toga promene koje prime\u0107ujemo posle 40. godine mogu predstavljati zbir prirodnog starenja, ranijeg fotoo\u0161te\u0107enja i hormonalnih uticaja.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-81bf37d thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"81bf37d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-c9325f4 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"c9325f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Za\u0161to se elasti\u010dnost ko\u017ee smanjuje?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b7d3776 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"b7d3776\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-4abccb9 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"4abccb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Elasti\u010dnost ko\u017ee zavisi od sposobnosti elasti\u010dnih vlakana da se nakon istezanja vrate prema prvobitnom obliku. Ova vlakna \u010dine slo\u017eenu mre\u017eu unutar dermisa, a njihova pravilna organizacija omogu\u0107ava ko\u017ei da prati pokrete lica i tela.<\/span><\/p><p><span style=\"font-weight: 400;\">Tokom prirodnog starenja struktura i funkcija elasti\u010dnih vlakana postepeno se menjaju. Dugogodi\u0161nje izlaganje UV zra\u010denju mo\u017ee dodatno o\u0161tetiti ovu mre\u017eu i dovesti do stanja koje se naziva solarna elastoza.<\/span><\/p><p><span style=\"font-weight: 400;\">Kod solarne elastoze u dermisu se nagomilava abnormalan elasti\u010dni materijal. Iako naziv mo\u017ee zvu\u010dati kao pove\u0107anje elastina, takvo tkivo nema normalna mehani\u010dka svojstva. Ko\u017ea zato mo\u017ee postati grublja, manje elasti\u010dna i izra\u017eenije naborana.<\/span><\/p><p><span style=\"font-weight: 400;\">Dugotrajno UV zra\u010denje predstavlja glavni faktor nastanka ovog poreme\u0107aja, jer o\u0161te\u0107uje kolagenska i elasti\u010dna vlakna dermisa.<\/span><\/p><p><span style=\"font-weight: 400;\">Ovo obja\u0161njava za\u0161to se posledice izlaganja suncu ne vide samo kao pigmentne mrlje. One mogu uticati i na strukturu ko\u017ee koja joj omogu\u0107ava da ostane \u010dvrsta i elasti\u010dna.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4744214 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"4744214\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-2193ffe flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"2193ffe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Za\u0161to gubitak \u010dvrstine nije isto \u0161to i gubitak volumena?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-303c596 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"303c596\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-1b39c1d flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"1b39c1d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Kada primetimo da su obrazi manje puni ili da je linija donje vilice izgubila raniju definiciju, lako je pomisliti da je problem isklju\u010divo u kolagenu. Me\u0111utim, izgled lica zavisi i od tkiva koja se nalaze ispod ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Potko\u017eno masno tkivo raspore\u0111eno je u razli\u010ditim anatomskim celinama koje doprinose obliku i puno\u0107i lica. Tokom starenja njihov volumen i polo\u017eaj mogu se menjati. Istovremeno dolazi do promena u potpornim ligamentima, mi\u0161i\u0107ima i ko\u0161tanim strukturama.<\/span><\/p><p><span style=\"font-weight: 400;\">Zbog toga se odre\u0111ene regije lica mogu \u010diniti praznijim, dok se u drugim delovima menja raspored mekih tkiva. Ove promene uti\u010du na konture lica \u010dak i kada je povr\u0161ina ko\u017ee dobro hidrirana.<\/span><\/p><p><span style=\"font-weight: 400;\">Kozmeti\u010dki preparati mogu pobolj\u0161ati hidrataciju, glatko\u0107u i pojedine karakteristike same ko\u017ee, ali ne mogu u potpunosti nadoknaditi promene volumena dubljih struktura.<\/span><\/p><p><span style=\"font-weight: 400;\">Ova razlika je va\u017ena kada biramo negu. Ako su glavni problem fine linije povezane sa suvo\u0107om, odgovaraju\u0107a hidratacija mo\u017ee dati primetno pobolj\u0161anje. Kada dominiraju izra\u017eene promene kontura, potrebno je razmotriti i dublje anatomske procese.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1ec5a7d thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"1ec5a7d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-12d617d flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"12d617d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kako hormonske promene uti\u010du na \u010dvrstinu ko\u017ee?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dda05c7 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"dda05c7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-a2b230d flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"a2b230d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Ko\u017ea je hormonski osetljiv organ, a estrogen ima va\u017enu ulogu u odr\u017eavanju njene strukture. U dermisu u\u010destvuje u procesima povezanim sa stvaranjem i odr\u017eavanjem kolagena, dok uti\u010de i na hidrataciju, debljinu i elasti\u010dnost ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Tokom perimenopauze jajnici postepeno menjaju na\u010din na koji odgovaraju na hormonalne signale. Ovulacija postaje manje predvidiva, a nivo estrogena mo\u017ee zna\u010dajno oscilirati. Nakon menopauze proizvodnja estrogena u jajnicima ostaje trajno ni\u017ea nego tokom reproduktivnog perioda.<\/span><\/p><p><span style=\"font-weight: 400;\">Ta promena hormonalnog okru\u017eenja mo\u017ee doprineti smanjenju sadr\u017eaja kolagena i promenama mehani\u010dkih svojstava ko\u017ee. Zbog toga neke \u017eene tokom menopauzalne tranzicije prime\u0107uju da im je ko\u017ea postala tanja, suvlja ili manje elasti\u010dna.<\/span><\/p><p><span style=\"font-weight: 400;\">Ipak, hormonske promene odvijaju se istovremeno sa prirodnim starenjem i kumulativnim UV o\u0161te\u0107enjem. Zato se kod svake \u017eene njihov doprinos razlikuje.<\/span><\/p><p><span style=\"font-weight: 400;\">U tekstu <span style=\"color: #ff0000;\">\u201e<\/span><\/span><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/drkozarevcosmedics.com\/perimenopauza-menopauza-koza\/\"><span style=\"font-weight: 400;\">Perimenopauza i menopauza: kako hormonske promene uti\u010du na ko\u017eu?<\/span><\/a><\/span><span style=\"font-weight: 400;\"><span style=\"color: #ff0000;\">\u201c<\/span> detaljnije smo objasnili kako se tokom ovog perioda menja proizvodnja hormona i za\u0161to se te promene mogu odraziti na ko\u017eu.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7219a6e thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"7219a6e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-15ef2be flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"15ef2be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Mo\u017ee li hidratantna krema u\u010diniti ko\u017eu \u010dvr\u0161\u0107om?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-169f995 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"169f995\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-f0cd066 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"f0cd066\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Kada ko\u017ei nedostaje voda, njena povr\u0161ina mo\u017ee izgledati grublje, a fine linije postaju izra\u017eenije. Odgovaraju\u0107a hidratacija pove\u0107ava sadr\u017eaj vode u povr\u0161inskim slojevima ko\u017ee i pobolj\u0161ava njihovu glatko\u0107u i meko\u0107u.<\/span><\/p><p><span style=\"font-weight: 400;\">Humektansi, poput hijaluronske kiseline i glicerina, vezuju vodu, dok emolijentni i okluzivni sastojci poma\u017eu o\u010duvanju za\u0161titne funkcije ko\u017ee i smanjenju gubitka vode.<\/span><\/p><p><span style=\"font-weight: 400;\">Zbog toga dobro odabrana hidratantna krema mo\u017ee u\u010diniti da ko\u017ea izgleda punije i ujedna\u010denije. Fine linije povezane sa suvo\u0107om mogu postati manje vidljive, a povr\u0161ina ko\u017ee prijatnija na dodir.<\/span><\/p><p><span style=\"font-weight: 400;\">Me\u0111utim, hidratacija deluje prvenstveno na odre\u0111ene karakteristike ko\u017ee i ne mo\u017ee u potpunosti nadoknaditi gubitak kolagena, promene elasti\u010dnih vlakana ili smanjenje volumena potko\u017enog tkiva.<\/span><\/p><p><span style=\"font-weight: 400;\">Ameri\u010dka akademija za dermatologiju u svojim<\/span><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/www.aad.org\/public\/everyday-care\/skin-care-secrets\/anti-aging\/selecting-anti-aging-products?utm_source=chatgpt.com\"> <span style=\"font-weight: 400;\">preporukama za izbor preparata protiv znakova starenja<\/span><\/a><\/span><span style=\"font-weight: 400;\"> posebno isti\u010de hidratantnu negu i fotoza\u0161titu kao osnovu rutine. Tako\u0111e savetuje da se dodatni preparati biraju prema konkretnom problemu koji \u017eelimo da pobolj\u0161amo.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58bfe04 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-image\" data-id=\"58bfe04\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"683\" src=\"https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-1024x683.jpg\" class=\"attachment-large size-large wp-image-9134\" alt=\"Pexels karola g\" srcset=\"https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-1024x683.jpg 1024w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-300x200.jpg 300w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-768x512.jpg 768w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-1536x1024.jpg 1536w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-2048x1365.jpg 2048w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-18x12.jpg 18w, https:\/\/drkozarevcosmedics.com\/wp-content\/uploads\/2026\/11\/pexels-karola-g-7321279-600x400.jpg 600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4041aea thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"4041aea\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-3e4f7eb flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"3e4f7eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Koji aktivni sastojci imaju smisla kod gubitka \u010dvrstine?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-52cddb0 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"52cddb0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-bb85956 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"bb85956\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Kada do\u0111e do opadanja \u010dvrstine ko\u017ee, prvi korak treba da bude razumevanje aktivnih sastojaka i njihovog delovanja. U nastavku teksta objasni\u0107u kako deluju retinoidi, peptidi i antioksidansi na vra\u0107anje \u010dvrstine ko\u017ei nakon 40. godine.<\/span><\/p><h3><b>Retinoidi<\/b><\/h3><p><span style=\"font-weight: 400;\">Retinoidi pripadaju grupi jedinjenja povezanih sa vitaminom A i me\u0111u najistra\u017eivanijim su aktivnim sastojcima u dermatologiji.<\/span><\/p><p><span style=\"font-weight: 400;\">Za pojedine retinoide, posebno tretinoin, postoje klini\u010dki i histolo\u0161ki dokazi o pobolj\u0161anju odre\u0111enih znakova fotoo\u0161te\u0107enja ko\u017ee. Njihovo dejstvo uklju\u010duje uticaj na obnavljanje epidermisa i procese povezane sa kolagenom u dermisu.<\/span><\/p><p><span style=\"font-weight: 400;\">Retinol se \u010desto nalazi u kozmeti\u010dkim preparatima i prolazi kroz vi\u0161e koraka konverzije pre nastanka retinoi\u010dne kiseline, biolo\u0161ki aktivnog oblika. Zbog toga njegovo dejstvo zavisi od formulacije, koncentracije i na\u010dina primene.<\/span><\/p><p><span style=\"font-weight: 400;\">Kod \u017eena koje \u017eele da rade na teksturi ko\u017ee i finim borama retinoidi mogu biti korisni, ali ih treba uvoditi postepeno. Izra\u017eena iritacija mo\u017ee ote\u017eati redovnu primenu i dodatno naru\u0161iti toleranciju ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">O pravilnom uvo\u0111enju detaljnije smo pisali u tekstu <span style=\"color: #ff0000;\">\u201e<\/span><\/span><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/drkozarevcosmedics.com\/kako-pravilno-koristiti-retinol\/\"><span style=\"font-weight: 400;\">Kako uvesti retinol u rutinu nege ko\u017ee i izbe\u0107i iritaciju?<\/span><\/a><span style=\"font-weight: 400;\">\u201c<\/span><\/span><\/p><h3><b>Peptidi<\/b><\/h3><p><span style=\"font-weight: 400;\">Peptidi su kratki lanci aminokiselina koji mogu imati razli\u010dite funkcije u organizmu. U kozmeti\u010dkim formulacijama koriste se razli\u010dite grupe peptida, me\u0111u kojima su i oni koji se istra\u017euju zbog mogu\u0107eg uticaja na signalne procese povezane sa ekstracelularnim matriksom.<\/span><\/p><p><span style=\"font-weight: 400;\">Jedan od najpoznatijih primera je GHK-Cu, bakarni tripeptid koji se prirodno nalazi u organizmu. Laboratorijska istra\u017eivanja pokazuju da mo\u017ee u\u010destvovati u procesima povezanim sa fibroblastima i remodelovanjem tkiva, \u0161to je podstaklo interesovanje za njegovu primenu u nezi ko\u017ee sa znacima starenja.<\/span><\/p><p><span style=\"font-weight: 400;\">Ipak, kod peptida je posebno va\u017eno razlikovati rezultate laboratorijskih istra\u017eivanja od klini\u010dki potvr\u0111enih efekata gotovih kozmeti\u010dkih preparata. Njihovo dejstvo zavisi i od stabilnosti, koncentracije i sposobnosti prolaska kroz ko\u017enu barijeru.<\/span><\/p><p><span style=\"font-weight: 400;\">Zbog toga naziv peptida na deklaraciji sam po sebi ne garantuje odre\u0111eni rezultat.<\/span><\/p><p><span style=\"font-weight: 400;\">U tekstu <span style=\"color: #ff0000;\">\u201e<\/span><\/span><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/drkozarevcosmedics.com\/ghk-cu-koza-posle-40\/\"><span style=\"font-weight: 400;\">GHK-Cu i ko\u017ea posle 40: \u0161ta zapravo znamo o bakarnim peptidima?<\/span><\/a><\/span><span style=\"font-weight: 400;\"><span style=\"color: #ff0000;\">\u201c<\/span> detaljnije smo objasnili zbog \u010dega je ovaj sastojak zanimljiv i \u0161ta trenutni dokazi zaista pokazuju.<\/span><\/p><h3><b>Antioksidansi<\/b><\/h3><p><span style=\"font-weight: 400;\">Tokom izlaganja UV zra\u010denju u ko\u017ei nastaju reaktivne vrste kiseonika koje mogu doprineti oksidativnom stresu. Ovi procesi u\u010destvuju u o\u0161te\u0107enju \u0107elijskih struktura i aktivaciji mehanizama povezanih sa razgradnjom ekstracelularnog matriksa.<\/span><\/p><p><span style=\"font-weight: 400;\">Antioksidansi mogu pomo\u0107i u neutralisanju odre\u0111enih reaktivnih molekula, zbog \u010dega imaju mesto u formulacijama namenjenim nezi fotoo\u0161te\u0107ene ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Vitamin C posebno je zanimljiv jer, pored antioksidativne uloge, u\u010destvuje i u biohemijskim procesima neophodnim za pravilno stvaranje kolagena.<\/span><\/p><p><span style=\"font-weight: 400;\">Me\u0111utim, topikalni vitamin C mora biti odgovaraju\u0107e formulisan kako bi ostao stabilan i mogao da dospe do ko\u017ee u aktivnom obliku. Zbog toga njegova efikasnost zavisi od hemijskog oblika, koncentracije i celokupne formulacije preparata.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fc2144f thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"fc2144f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-6af2d5c flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"6af2d5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Mo\u017ee li kozmetika da podstakne stvaranje kolagena?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f1b0b8b thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"f1b0b8b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-648ca94 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"648ca94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Odre\u0111eni aktivni sastojci mogu uticati na procese povezane sa stvaranjem i remodelovanjem kolagena. Za pojedine retinoide postoje kvalitetni klini\u010dki dokazi o pobolj\u0161anju odre\u0111enih znakova fotoo\u0161te\u0107enja, dok se efekti mnogih drugih sastojaka jo\u0161 istra\u017euju.<\/span><\/p><p><span style=\"font-weight: 400;\">Va\u017eno je razumeti i vremenski okvir. Promene u strukturi ko\u017ee zahtevaju vreme, jer se stvaranje i remodelovanje kolagena odvijaju postepeno. Zbog toga rezultate ne treba procenjivati nakon nekoliko dana kori\u0161\u0107enja preparata.<\/span><\/p><p><span style=\"font-weight: 400;\">Tako\u0111e, pobolj\u0161anje hidratacije mo\u017ee biti vidljivo mnogo ranije od promena povezanih sa strukturom dermisa. To su razli\u010diti efekti i ne treba ih me\u0111usobno me\u0161ati.<\/span><\/p><p><span style=\"font-weight: 400;\">Kada biramo preparat, korisno je znati na koji proces poku\u0161avamo da uti\u010demo i koliko dobri dokazi postoje za konkretnu formulaciju.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-db52557 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"db52557\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-9a063ef flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"9a063ef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kada profesionalni tretmani imaju vi\u0161e smisla?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ae603d thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"7ae603d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-5bb3a68 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"5bb3a68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Ako su promene prvenstveno povezane sa povr\u0161inskom suvo\u0107om, finim linijama i neujedna\u010denom teksturom, odgovaraju\u0107a ku\u0107na nega mo\u017ee pru\u017eiti zna\u010dajno pobolj\u0161anje.<\/span><\/p><p><span style=\"font-weight: 400;\">Kod izra\u017eenijih bora, opu\u0161tenosti ili promena kontura lica potrebno je razmotriti i strukture koje se nalaze dublje od epidermisa.<\/span><\/p><p><span style=\"font-weight: 400;\">U zavisnosti od problema, dermatolog mo\u017ee proceniti da li postoje indikacije za odre\u0111ene laserske, radiofrekventne, ultrazvu\u010dne ili druge procedure. Neke od njih usmerene su na remodelovanje tkiva, dok druge imaju za cilj korekciju volumena ili odre\u0111enih bora.<\/span><\/p><p><span style=\"font-weight: 400;\">Njihovi mehanizmi, rezultati, rizici i periodi oporavka razlikuju se, zbog \u010dega izbor treba prilagoditi anatomiji lica i ciljevima konkretne osobe.<\/span><\/p><p><span style=\"font-weight: 400;\">AAD u<\/span><span style=\"color: #ff0000;\"><a style=\"color: #ff0000;\" href=\"https:\/\/www.aad.org\/public\/everyday-care\/sun-protection\/sun-damage-skin\/wrinkles-sun-damage-can-be-treated?utm_source=chatgpt.com\"> <span style=\"font-weight: 400;\">pregledu mogu\u0107nosti tretiranja fotoo\u0161te\u0107ene ko\u017ee<\/span><\/a><\/span><span style=\"font-weight: 400;\"> obja\u0161njava da razli\u010dite promene, poput bora, pigmentacija i opu\u0161tenosti, zahtevaju razli\u010dite terapijske pristupe.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e60f507 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"e60f507\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-e8e1e4a flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"e8e1e4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Za\u0161to je SPF va\u017ean za o\u010duvanje \u010dvrstine ko\u017ee?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-482e37c thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"482e37c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-22c977b flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"22c977b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">UV zra\u010denje predstavlja jedan od najva\u017enijih spolja\u0161njih faktora koji ubrzavaju promene kolagena i elasti\u010dnih vlakana. Dugotrajno izlaganje suncu doprinosi razgradnji komponenti dermisa, zbog \u010dega se na ko\u017ei postepeno pojavljuju bore, promenjena tekstura i smanjena elasti\u010dnost.<\/span><\/p><p><span style=\"font-weight: 400;\">Svakodnevna fotoza\u0161tita poma\u017ee da se smanji dodatno UV o\u0161te\u0107enje. Posebno je va\u017ena kada ve\u0107 koristimo retinoide, antioksidanse ili druge aktivne sastojke sa ciljem pobolj\u0161anja znakova fotoo\u0161te\u0107enja.<\/span><\/p><p><span style=\"font-weight: 400;\">Preporu\u010duje se \u00a0\u0161irokospektralni SPF 30 ili vi\u0161i, uz odgovaraju\u0107u za\u0161titnu ode\u0107u, hlad i ponovno nano\u0161enje preparata kada je potrebno. Ove mere predstavljaju osnovu prevencije prevremenog starenja ko\u017ee.<\/span><\/p><p><span style=\"font-weight: 400;\">Zato fotoza\u0161titu treba posmatrati kao dugoro\u010dan deo rutine, a ne kao dodatak koji koristimo samo tokom leta.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ba20513 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"ba20513\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-bc80d7f flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"bc80d7f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Kako napraviti rutinu za ko\u017eu koja gubi \u010dvrstinu?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dce92f4 thegem-e-con-layout-elementor e-flex e-con-boxed e-con e-parent\" data-id=\"dce92f4\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t\t<div class=\"e-con-inner\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-1829bbe flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-text-editor\" data-id=\"1829bbe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\r\n\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Pre izbora novih preparata korisno je proceniti koja promena ti najvi\u0161e smeta.<\/span><\/p><p><span style=\"font-weight: 400;\">Ako je ko\u017ea postala suvlja, a fine linije izra\u017eenije, prvi korak mo\u017ee biti prilago\u0111avanje hidratacije i \u010di\u0161\u0107enja. Ako dominiraju neujedna\u010dena tekstura i znaci fotoo\u0161te\u0107enja, odre\u0111eni aktivni sastojci mogu imati vi\u0161e smisla.<\/span><\/p><p><span style=\"font-weight: 400;\">Kada su najve\u0107a promena konture lica ili gubitak volumena, va\u017eno je razumeti da na njihov izgled uti\u010du i dublje strukture.<\/span><\/p><p><span style=\"font-weight: 400;\">U svakodnevnoj rutini osnova ostaje blago \u010di\u0161\u0107enje, hidratacija prema potrebama ko\u017ee i redovna fotoza\u0161tita. Zatim se bira aktivni sastojak koji odgovara konkretnom cilju i koji ko\u017ea mo\u017ee dobro da podnosi.<\/span><\/p><p><span style=\"font-weight: 400;\">Takav pristup omogu\u0107ava da svaki proizvod ima jasnu ulogu, a da rutina ostane dovoljno jednostavna za dugoro\u010dnu primenu.<\/span><\/p>\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-36ad7a2 e-con-full thegem-e-con-layout-elementor e-flex e-con e-child\" data-id=\"36ad7a2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;thegem_container_layout&quot;:&quot;elementor&quot;}\">\r\n\t\t\t\t<div class=\"elementor-element elementor-element-2c3beac flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-heading\" data-id=\"2c3beac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">FAQ \u2013 naj\u010de\u0161\u0107a pitanja o gubitku \u010dvrstine ko\u017ee<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-07a1869 flex-horizontal-align-default flex-horizontal-align-tablet-default flex-horizontal-align-mobile-default flex-vertical-align-default flex-vertical-align-tablet-default flex-vertical-align-mobile-default elementor-widget elementor-widget-thegem-accordion\" data-id=\"07a1869\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;thegem_elementor_preset&quot;:&quot;simple_solid&quot;,&quot;title_position_mobile&quot;:&quot;left&quot;,&quot;title_position&quot;:&quot;left&quot;}\" data-widget_type=\"thegem-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\t\t<div class=\"gem-tta-container\" data-vc-action=\"collapseAll\">\n\t\t\t<div class=\"gem-tta-general gem-tta gem-tta-accordion gem-tta-color-thegem gem-tta-style-simple_solid gem-tta-shape-rounded gem-tta-o-shape-group gem-tta-controls-align-left\">\n\t\t\t\t<div class=\"gem-tta-panels-container\">\n\t\t\t\t\t<div class=\"gem-tta-panels\">\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t<div id=\"section-07a1869-1\" class=\"gem-tta-panel \" data-vc-content=\".gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-heading\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"gem-tta-panel-title gem-tta-controls-icon-position-left\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"#section-07a1869-1\" data-vc-accordion data-vc-container=\".gem-tta-container\">\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-title-text\">\n\t\t\t\t\t\t\t\t\t\t\t\tZa\u0161to mi ko\u017ea deluje opu\u0161tenije posle 40?\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-opened\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-closed\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"gem-text-output\"><p><span style=\"font-weight: 400;\">Sa godinama se menjaju struktura kolagena, elasti\u010dna vlakna i aktivnost \u0107elija koje odr\u017eavaju dermis. Istovremeno se menjaju raspored potko\u017enog masnog tkiva i druge potporne strukture lica. Kod \u017eena hormonalne promene tokom perimenopauze mogu dodatno uticati na kolagen i elasti\u010dnost ko\u017ee.<\/span><\/p><\/div>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t<div id=\"section-07a1869-2\" class=\"gem-tta-panel \" data-vc-content=\".gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-heading\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"gem-tta-panel-title gem-tta-controls-icon-position-left\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"#section-07a1869-2\" data-vc-accordion data-vc-container=\".gem-tta-container\">\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-title-text\">\n\t\t\t\t\t\t\t\t\t\t\t\tDa li krema mo\u017ee da zategne opu\u0161tenu ko\u017eu?\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-opened\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-closed\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"gem-text-output\"><p><span style=\"font-weight: 400;\">Hidratantna krema mo\u017ee pobolj\u0161ati glatko\u0107u, puno\u0107u povr\u0161inskih slojeva i izgled finih linija povezanih sa suvo\u0107om. Odre\u0111eni aktivni sastojci mogu doprineti pobolj\u0161anju pojedinih znakova fotoo\u0161te\u0107enja, ali izra\u017eene promene volumena i kontura lica zahtevaju druga\u010diju procenu.<\/span><\/p><\/div>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t<div id=\"section-07a1869-3\" class=\"gem-tta-panel \" data-vc-content=\".gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-heading\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"gem-tta-panel-title gem-tta-controls-icon-position-left\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"#section-07a1869-3\" data-vc-accordion data-vc-container=\".gem-tta-container\">\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-title-text\">\n\t\t\t\t\t\t\t\t\t\t\t\tDa li retinol uti\u010de na kolagen?\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-opened\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-closed\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"gem-text-output\"><p><span style=\"font-weight: 400;\">Retinol pripada grupi retinoida, za koju postoje dokazi o uticaju na procese povezane sa kolagenom. Najsna\u017eniji klini\u010dki dokazi za fotoo\u0161te\u0107enu ko\u017eu odnose se na pojedine retinoide, naro\u010dito tretinoin. Efekti kozmeti\u010dkog retinola zavise od formulacije, koncentracije i pravilne upotrebe.<\/span><\/p><p><br style=\"font-weight: 400;\" \/><br style=\"font-weight: 400;\" \/><\/p><\/div>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t<div id=\"section-07a1869-4\" class=\"gem-tta-panel \" data-vc-content=\".gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-heading\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"gem-tta-panel-title gem-tta-controls-icon-position-left\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"#section-07a1869-4\" data-vc-accordion data-vc-container=\".gem-tta-container\">\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-title-text\">\n\t\t\t\t\t\t\t\t\t\t\t\tDa li peptidi mogu pobolj\u0161ati elasti\u010dnost ko\u017ee?\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-opened\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-closed\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"gem-text-output\"><p><span style=\"font-weight: 400;\">Odre\u0111eni peptidi imaju zanimljive biolo\u0161ke mehanizme i preklini\u010dke rezultate, ali kvalitet i koli\u010dina klini\u010dkih dokaza razlikuju se izme\u0111u pojedinih sastojaka. Zato je va\u017eno proceniti konkretan peptid i formulaciju, umesto o\u010dekivati isti efekat od svih preparata sa peptidima.<\/span><\/p><\/div>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t<div id=\"section-07a1869-5\" class=\"gem-tta-panel \" data-vc-content=\".gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-heading\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"gem-tta-panel-title gem-tta-controls-icon-position-left\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"#section-07a1869-5\" data-vc-accordion data-vc-container=\".gem-tta-container\">\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-title-text\">\n\t\t\t\t\t\t\t\t\t\t\t\tKada treba razmotriti dermatolo\u0161ki tretman?\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-opened\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"gem-tta-controls-icon gem-tta-controls-icon-closed\">\n\t\t\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"gem-tta-panel-body\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"gem-text-output\"><p><span style=\"font-weight: 400;\">Dermatolo\u0161ki pregled ima smisla kada su promene izra\u017eenije, kada ku\u0107na nega ne daje o\u010dekivani rezultat ili kada \u017eeli\u0161 da razume\u0161 koje su mogu\u0107nosti za korekciju bora, opu\u0161tenosti i kontura lica. Pregled poma\u017ee da se utvrdi koje strukture najvi\u0161e doprinose promeni i koji pristup ima realne izglede za pobolj\u0161anje.<\/span><\/p><\/div>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<script type=\"application\/ld+json\">{\"@context\": \"https:\/\/schema.org\",\"@type\": \"FAQPage\",\"mainEntity\": [{\"@type\": \"Question\",\"name\": \"Za\u0161to mi ko\u017ea deluje opu\u0161tenije posle 40?\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"<p><span style=\\\"font-weight: 400;\\\">Sa godinama se menjaju struktura kolagena, elasti\\u010dna vlakna i aktivnost \\u0107elija koje odr\\u017eavaju dermis. Istovremeno se menjaju raspored potko\\u017enog masnog tkiva i druge potporne strukture lica. Kod \\u017eena hormonalne promene tokom perimenopauze mogu dodatno uticati na kolagen i elasti\\u010dnost ko\\u017ee.<\\\/span><\\\/p>\"}},{\"@type\": \"Question\",\"name\": \"Da li krema mo\u017ee da zategne opu\u0161tenu ko\u017eu?\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"<p><span style=\\\"font-weight: 400;\\\">Hidratantna krema mo\\u017ee pobolj\\u0161ati glatko\\u0107u, puno\\u0107u povr\\u0161inskih slojeva i izgled finih linija povezanih sa suvo\\u0107om. Odre\\u0111eni aktivni sastojci mogu doprineti pobolj\\u0161anju pojedinih znakova fotoo\\u0161te\\u0107enja, ali izra\\u017eene promene volumena i kontura lica zahtevaju druga\\u010diju procenu.<\\\/span><\\\/p>\"}},{\"@type\": \"Question\",\"name\": \"Da li retinol uti\u010de na kolagen?\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"<p><span style=\\\"font-weight: 400;\\\">Retinol pripada grupi retinoida, za koju postoje dokazi o uticaju na procese povezane sa kolagenom. Najsna\\u017eniji klini\\u010dki dokazi za fotoo\\u0161te\\u0107enu ko\\u017eu odnose se na pojedine retinoide, naro\\u010dito tretinoin. Efekti kozmeti\\u010dkog retinola zavise od formulacije, koncentracije i pravilne upotrebe.<\\\/span><\\\/p><p><br style=\\\"font-weight: 400;\\\" \\\/><br style=\\\"font-weight: 400;\\\" \\\/><\\\/p>\"}},{\"@type\": \"Question\",\"name\": \"Da li peptidi mogu pobolj\u0161ati elasti\u010dnost ko\u017ee?\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"<p><span style=\\\"font-weight: 400;\\\">Odre\\u0111eni peptidi imaju zanimljive biolo\\u0161ke mehanizme i preklini\\u010dke rezultate, ali kvalitet i koli\\u010dina klini\\u010dkih dokaza razlikuju se izme\\u0111u pojedinih sastojaka. Zato je va\\u017eno proceniti konkretan peptid i formulaciju, umesto o\\u010dekivati isti efekat od svih preparata sa peptidima.<\\\/span><\\\/p>\"}},{\"@type\": \"Question\",\"name\": \"Kada treba razmotriti dermatolo\u0161ki tretman?\",\"acceptedAnswer\": {\"@type\": \"Answer\",\"text\": \"<p><span style=\\\"font-weight: 400;\\\">Dermatolo\\u0161ki pregled ima smisla kada su promene izra\\u017eenije, kada ku\\u0107na nega ne daje o\\u010dekivani rezultat ili kada \\u017eeli\\u0161 da razume\\u0161 koje su mogu\\u0107nosti za korekciju bora, opu\\u0161tenosti i kontura lica. Pregled poma\\u017ee da se utvrdi koje strukture najvi\\u0161e doprinose promeni i koji pristup ima realne izglede za pobolj\\u0161anje.<\\\/span><\\\/p>\"}}]}<\/script>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Mo\u017eda si primetila da ko\u017ea na obrazima vi\u0161e nema istu puno\u0107u, da su fine linije izra\u017eenije ili da kontura donje&#8230;<\/p>","protected":false},"author":3,"featured_media":9138,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"slim_seo":{"title":"Gubitak \u010dvrstine ko\u017ee posle 40","description":"Za\u0161to ko\u017ea gubi \u010dvrstinu i elasti\u010dnost posle 40? Saznaj kako se menjaju kolagen i elastin i \u0161ta mogu retinol, peptidi i pravilna nega."},"footnotes":""},"categories":[74],"tags":[],"class_list":["post-9075","post","type-post","status-publish","format-standard","has-post-thumbnail","category-dr-kozarev"],"menu_order":0,"_links":{"self":[{"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/posts\/9075","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/comments?post=9075"}],"version-history":[{"count":4,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/posts\/9075\/revisions"}],"predecessor-version":[{"id":9139,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/posts\/9075\/revisions\/9139"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/media\/9138"}],"wp:attachment":[{"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/media?parent=9075"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/categories?post=9075"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drkozarevcosmedics.com\/en\/wp-json\/wp\/v2\/tags?post=9075"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}